In Vitro Study Assessment of the Effect of 3VM1000 Suspension on SARS-CoV-2 Infectivity.
The purpose of this study is to assess the effect of 3VM1000 Suspension on SAR CoV-2 infectivity of host cells in vitro. Pre-challenge study to determine if 3VM100 Suspension is effective in killing SARS-CoV-2 and reduce its infectivity in vitro.
SOW (Click here)
Final In Vitro Study test report (Click here)
In Vivo Study To determine the anti-SARS-CoV-2 effect of 3VM-1000 suspension in K18 hACE‑2 mice.
This study is designed to test in vivo toxicity and efficacy of 3VM-1000 suspension in a mouse
model of SARS-CoV-2 infection by measuring the viral load and survival. To determine the anti-SARS-CoV-2 effect of 3VM-1000 suspension in K18 hACE-2 mice.
Aim 1: To determine in vivo toxicity of 3VM-1000 suspension solution in K18-hACE-2 mice
SOW (click here)
Final Results (click here)
Aim 2: In vivo assessment of 3VM-1000 suspension on SARS-CoV-2 infectivity
Currently, Texas Biomedical Research Institute is conducting Aim 2 study using 3VM-1000 suspension solution for the effectiveness to treat SARS-CoV2.